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5–four μmol/L range,[156][157] the focus of serotonin in synaptic vesicles was measured at 270 mM.[182] pursuing vesicular release, the ensuing concentration of serotonin within the synaptic cleft, to which serotonin receptors are exposed, is believed to generally be about three hundred μmol/L. Thus, even though in vitro receptor binding affi
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